Song Chart: May 2010 
Song Chart: May 2010 | Switch to Albums |
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| # | Artist | Song | May 2010 Peak | Indic Revenue | |||||
| us | uk | de | fr | ca | au | ||||
| 1 | Lady GaGa & Beyonce | Telephone | 7 | 11 | 6 | 5 | 9 | 12 | 1839.370 |
| 2 | Train | Hey, Soul Sister | 3 | 18 | 7 | - | 3 | 2 | 1788.287 |
| 3 | Rihanna | Rude Boy | 2 | 17 | 17 | 20 | 8 | 16 | 1485.667 |
| 4 | Taio Cruz & Ludacris | Break Your Heart | 3 | - | 7 | 2 | 1 | 2 | 1430.801 |
| 5 | Usher & will.i.am | OMG | 1 | 2 | - | - | 3 | 1 | 1343.667 |
| 6 | Jason Derulo | In My Head | 6 | 23 | 9 | - | 5 | 4 | 1273.851 |
| 7 | BoB & Bruno Mars | Nothin' On You | 1 | 1 | - | - | 13 | 3 | 1215.558 |
| 8 | Justin Bieber & Ludacris | Baby | 16 | 18 | 48 | 1 | 24 | 3 | 1179.429 |
| 9 | Stromae | Alors on danse | - | - | 4 | 1 | - | - | 1114.659 |
| 10 | Ke$ha | Tik-Toc | 17 | 53 | 12 | 19 | 18 | 30 | 1111.765 |
| 11 | Adam Lambert | What Do You Want From Me? | 10 | - | 5 | - | 6 | 4 | 1089.837 |
| 12 | Timbaland & Katy Perry | If We Ever Meet Again | 37 | 36 | 20 | 5 | 4 | 11 | 1045.397 |
| 13 | Lady GaGa | Bad Romance | 24 | 32 | 32 | 25 | 23 | 28 | 993.989 |
| 14 | Lady Antebellum | Need You Now | 4 | 21 | - | - | 4 | - | 955.032 |
| 15 | Mehrzad Marashi | Don't Believe | - | - | 1 | - | - | - | 940.108 |
| 16 | David Guetta & Kid Cudi | Memories | - | 15 | 9 | 15 | 21 | 15 | 903.413 |
| 17 | Ke$ha | Your Love Is My Drug | 7 | 18 | - | - | 6 | 8 | 847.888 |
| 18 | Lena Meyer-Landrut | Satellite | - | - | 2 | - | - | - | 834.778 |
| 19 | Selena Gomez & The Scene | Naturally | 35 | 10 | 14 | - | 48 | - | 798.054 |
| 20 | The Black Eyed Peas | I Gotta Feeling | 38 | 43 | 38 | - | 19 | 49 | 785.111 |
| 21 | Unheilig | Geboren um zu leben | - | - | 3 | - | - | - | 757.472 |
| 22 | BoB & Hayley Williams | Airplanes | 3 | - | - | - | 7 | 2 | 750.348 |
| 23 | Lady GaGa | Alejandro | 8 | 40 | - | - | 4 | 2 | 739.312 |
| 24 | Timbaland & Justin Timberlake | Carry Out | 19 | 8 | - | - | 19 | - | 737.996 |
| 25 | OneRepublic | All The Right Moves | 22 | - | 24 | - | 36 | - | 712.525 |
| 26 | Cheryl Cole | Fight For This Love | - | 70 | 8 | 11 | - | - | 701.863 |
| 27 | The Black Eyed Peas | Rock That Body | 24 | 32 | 16 | 11 | - | 44 | 698.515 |
| 28 | Drake | Over | 14 | 50 | - | - | 17 | - | 688.816 |
| 29 | The Black Eyed Peas | Imma Be | 11 | 75 | - | - | 32 | 17 | 687.391 |
| 30 | Sean Kingston & Justin Bieber | Eenie Meenie | 15 | 10 | - | - | 20 | 11 | 655.193 |
| 31 | Jay-Z & Mr Hudson | Young Forever | 10 | - | - | - | 21 | - | 651.709 |
| 32 | Young Money & Lloyd | BedRock | 21 | 20 | - | - | 31 | - | 602.633 |
| 33 | The Script | Breakeven | 12 | - | - | - | 20 | - | 591.732 |
| 34 | David Guetta & Akon | Sexy Chick (Sexy Bitch) | 38 | 96 | 57 | 80 | 36 | 50 | 584.037 |
| 35 | Ludacris & Nicki Minaj | My Chick Bad | 11 | - | - | - | - | - | 577.009 |
| 36 | Owl City | Fireflies | - | 29 | 30 | 21 | 39 | 19 | 564.201 |
| 37 | Ke$ha | Blah, Blah, Blah | 54 | 79 | 11 | - | 41 | 20 | 563.478 |
| 38 | Iyaz | Replay | - | 58 | 11 | 12 | - | 23 | 556.582 |
| 39 | Christina Aguilera | Not Myself Tonight | 23 | 12 | - | - | 11 | 22 | 547.377 |
| 40 | Mark Medlock | Real Love | - | - | 3 | - | - | - | 536.007 |
| 41 | Michael Buble | Haven't Met You Yet | 26 | 38 | - | - | 19 | - | 533.130 |
| 42 | Kevin Rudolf & Lil' Wayne | I Made It (Cash Money Heroes) | 21 | - | - | - | - | 7 | 525.284 |
| 43 | K'naan | Wavin' Flag | - | 16 | 1 | - | 15 | - | 524.483 |
| 44 | Trey Songz & Fabolous | Say Aah | 15 | - | - | - | 47 | - | 505.709 |
| 45 | Iyaz | Solo | 32 | 3 | - | - | - | 48 | 443.227 |
| 46 | Usher | Hey Daddy (Daddy's Home) | 24 | - | - | - | - | - | 432.579 |
| 47 | Lady Antebellum | American Honey | 25 | - | - | - | 50 | - | 429.277 |
| 48 | La Roux | Bulletproof! | 19 | - | - | - | - | - | 427.490 |
| 49 | Eminem | Not Afraid | 1 | 5 | - | - | 1 | 4 | 425.603 |
| 50 | Shakira | Gypsy | 65 | - | 13 | - | - | - | 416.658 |