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| # | Artist | Song | Position This Day | Indic Revenue | |||||
| us | uk | de | fr | ca | au | ||||
| 1 | Madonna & Justin Timberlake | Four Minutes | 8 | 8 | 4 | 5 | 1 | 2 | 108.039 |
| 2 | Usher & Young Jeezy | Love In This Club | 6 | 12 | 8 | 9 | 7 | 11 | 91.904 |
| 3 | Duffy | Mercy | 33 | 21 | 3 | 2 | 11 | 35 | 86.285 |
| 4 | Leona Lewis | Bleeding Love | 2 | - | 21 | 23 | 3 | 22 | 71.202 |
| 5 | Rihanna | Take A Bow | 4 | 2 | - | - | 4 | 6 | 68.691 |
| 6 | Lil' Wayne | Lollipop | 1 | 26 | - | - | 10 | - | 67.482 |
| 7 | Estelle & Kanye West | American Boy | 65 | 17 | 9 | - | 28 | 4 | 62.678 |
| 8 | Sara Bareilles | Love Song | 20 | 6 | 22 | - | 20 | 10 | 59.108 |
| 9 | Flo-Rida & T-Pain | Low | 24 | 19 | 26 | 33 | 19 | 5 | 55.716 |
| 10 | Jordin Sparks & Chris Brown | No Air | 5 | 74 | - | - | 9 | 3 | 51.664 |